What is a key therapeutic intervention for patients with hyperglycemic crises?

In cases of hyperglycemic crises, such as diabetic ketoacidosis (DKA) or hyperglycemic hyperosmolar state (HHS), rapid and effective management is critical. Intravenous insulin administration is essential for lowering blood glucose levels quickly, as it facilitates the uptake of glucose into cells and inhibits hepatic glucose production. This intervention addresses the primary metabolic derangement seen in these crises.

Fluid resuscitation is also a crucial component of therapy for patients experiencing hyperglycemic crises. These patients typically present with dehydration due to osmotic diuresis caused by high blood sugar levels. Administering intravenous fluids helps to restore intravascular volume, improve renal perfusion, and dilute the hyperglycemia.

Together, intravenous insulin and fluid resuscitation work synergistically to stabilize the patient's condition and prevent complications associated with hyperglycemic crises. This treatment approach is well-established in clinical guidelines for managing such emergencies.